MAP1LC3A Monoclonal Antibody + Cell Lysate Kit
Applications
Reactivity
| Overview | |
| Catalog # | bsm-90005R |
| Product Name | MAP1LC3A Monoclonal Antibody + Cell Lysate Kit |
| Applications | WB, IC |
| Specificity | Knockdown Validated |
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | A synthesized peptide derived from human MAP1LC3A |
| Immunogen Range | 1-34/121 |
| Clonality | Monoclonal |
| Clone # | 23GB1960 |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Affinity Purified |
| Storage Buffer | Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide. |
| Storage Condition | -20 °C |
| Target | |
| Gene ID | 84557 |
| Swiss Prot | Q9H492 |
| Synonyms | MAP1LC3A; Microtubule Associated Protein 1 Light Chain 3 Alpha; MAP1BLC3; MAP1ALC3; ATG8E; LC3A; LC3; Microtubule-Associated Proteins 1A/1B Light Chain 3A; Autophagy-Related Ubiquitin-Like Modifier LC3 A; MAP1 Light Chain 3-Like Protein 1; MAP1A/MAP1B Light Chain 3 A; MAP1A/MAP1B LC3 A; Microtubule-Associated Protein 1 Light Chain 3 Alpha; Microtubule-Associated Proteins 1A/1B Light Chain 3; Autophagy-Related Protein LC3 A; MAP1A/1B Light Chain 3 A |
| Background | Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover. Cell Line: HeLa Knockdown technology: shRNA Knockdown |
| Application Dilution | |
| WB | : 1:1000-1:20000 |
| IC | IC: 1:1000 |
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