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Thrombomodulin Polyclonal Antibody, APC-Cy5.5 Conjugated

Applications

  • WB
  • FCM

Reactivity

  • Human

Predicted Reactivity

  • Mouse
  • Rat
  • Dog
  • Rabbit
Overview
Catalog # bs-20396R-APC-Cy5.5
Product Name Thrombomodulin Polyclonal Antibody, APC-Cy5.5 Conjugated
Applications WB, FCM
Reactivity Human
Predicted Reactivity Mouse, Rat, Dog, Rabbit
Specifications
Conjugation APC-Cy5.5
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Thrombomodulin
Immunogen Range 51-150/575
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 7056
Swiss Prot P07204
Subcellular location Cell membrane
Synonyms Thrombomodulin; CD 141; CD141; CD141 antigen; Fetomodulin; THBD; THRM; TM; AHUS 6; AHUS6; BDCA 3; BDCA3; THPH12; TRBM_HUMAN.
Background Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.
Application Dilution
WB 1:300-5000
FCM 1:20-100