Thrombomodulin Polyclonal Antibody

$Lane 1: Human Huvec cell lysates; Lane 2: Human A549 cell lysates probed with Thrombomodulin Polyclonal Antibody, Unconjugated (bs-20396R) at 1:200 dilution and 4\u00b0C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.$

Lane 1: Human Huvec cell lysates; Lane 2: Human A549 cell lysates probed with Thrombomodulin Polyclonal Antibody, Unconjugated (bs-20396R) at 1:200 dilution and 4\u00b0C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.

Applications

Reactivity

Human

Predicted Reactivity

Mouse
Rat
Dog
Rabbit

Overview
Catalog #	bs-20396R
Product Name	Thrombomodulin Polyclonal Antibody
Applications	WB, FCM
Reactivity	Human
Predicted Reactivity	Mouse, Rat, Dog, Rabbit
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from human Thrombomodulin
Immunogen Range	51-150/575
Clonality	Polyclonal
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	7056
Swiss Prot	P07204
Subcellular location	Cell membrane
Synonyms	Thrombomodulin; CD 141; CD141; CD141 antigen; Fetomodulin; THBD; THRM; TM; AHUS 6; AHUS6; BDCA 3; BDCA3; THPH12; TRBM_HUMAN.
Background	Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.
Application Dilution
WB	1:300-5000
FCM	1:20-100