Overview |
bs-5449R-Cy5.5 |
IGF1R (Tyr1165 + Tyr1166) Antibody, Cy5.5 Conjugated |
FCM |
Mouse, Rat |
Human, Dog, Cow, Pig, Chicken |
Specifications |
Cy5.5 |
Rabbit |
KLH conjugated synthetic phosphopeptide derived from human IGF1R around the phosphorylation site of Tyr1165+Tyr1166 |
Tyr1165 + Tyr1166 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
3480 |
P08069 |
Cell membrane |
IGF-1R Tyr1165/Tyr1166; IGF1R phospho Y1165+Y1166; IGF1R phospho Tyr1165+Tyr1166; p-IGF1R Tyr1165+Tyr1166; CD221; CD221 antigen; IGF 1 receptor; IGF 1R; IGF I receptor; IGF1R; IGFIR; IGFIRC; Insulin like growth factor 1 receptor; Insulin like growth factor 1 receptor precursor; JTK13; MGC142170; MGC142172; IGF1 Receptor; IGF1R_HUMAN. |
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq, Jul 2008]. |
Application Dilution |
FCM |
1:20-100 |