Overview |
bs-13188R-PE-Cy7 |
FMRP (Ser500) Polyclonal Antibody, PE-Cy7 Conjugated |
WB |
Human, Mouse, Rat, Zebrafish |
Dog, Cow, Sheep, Pig, Chicken, Rabbit, Guinea Pig |
Specifications |
PE-Cy7 |
Rabbit |
KLH conjugated synthetic phosphopeptide derived from human FMRP around the phosphorylation site of Ser500 |
Ser500 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
2332 |
Q06787 |
Cytoplasm, Nucleus |
POF; FMRP; POF1; FRAXA; Fragile X mental retardation protein 1; Protein FMR-1; FMR1 |
Translation repressor. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm. Binds strongly to poly(G), binds moderately to poly(U) but shows very little binding to poly(A) or poly(C). |
Application Dilution |
WB |
1:300-5000 |