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mouse CD45R/APC-Cy5.5

Applications

  • FCM

Reactivity

  • Mouse
Overview
Catalog # bsm-30307A-APC-CY5.5
Product Name mouse CD45R/APC-Cy5.5
Applications FCM
Reactivity Mouse
Specifications
Conjugation Unconjugated
Host Rat
Clonality Monoclonal
Clone # 3B6
Isotype IgG2a/Kappa
Concentration n/a
Purification Affinity purified by Protein G
Storage Buffer 0.01M PBS, 0.5%BSA, 0.03% Proclin300
Storage Condition Store at 2-8℃. Protect from light. Avoid freezing.
Target
Gene ID 19264
Swiss Prot P06800
Background CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.
Application Dilution
FCM 1:20-100