mouse Ly-49C/F/H/I/FITC

Overview
Catalog #	bsm-30282H-FITC
Product Name	mouse Ly-49C/F/H/I/FITC
Applications	FCM
Reactivity	Mouse
Specifications
Conjugation	Unconjugated
Host	Hamster
Clonality	Monoclonal
Clone #	3F12
Isotype	IgG1
Concentration	n/a
Purification	Affinity purified by Protein G
Storage Buffer	0.01M PBS, 0.5%BSA, 0.03% Proclin300
Storage Condition	Store at 2-8℃. Protect from light. Avoid freezing.
Target
Gene ID	16634
Swiss Prot	Q64329
Synonyms	KLRA3_MOUSE; 5E6; Killer cell lectin like receptor 3; Killer cell lectin like receptor subfamily A member 3; KLRA 3; Ly 49c; Ly49C; Lymphocyte antigen 49c; MGC123910; Natural killer cell associated antigen 2; Nk 2; NK 2.1; Nk2; Nk2.1; OTTMUSP00000026267; T cell surface glycoprotein Ly 49C.
Background	KLRA3 (also known as Ly49C) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA3 is thought to be an inhibitory receptor, recognizing peptide–receptive H-2Kb.
Application Dilution
FCM	1:20-100