human TDT/PE

Overview
Catalog #	bsm-30223M-PE
Product Name	human TDT/PE
Applications	FCM
Reactivity	Human
Specifications
Conjugation	Unconjugated
Host	Mouse
Clonality	Monoclonal
Clone #	3H2
Isotype	IgG1/Kappa
Concentration	n/a
Purification	Affinity purified by Protein G
Storage Buffer	0.01M PBS, 0.5%BSA, 0.03% Proclin300
Storage Condition	Store at 2-8℃. Protect from light. Avoid freezing.
Target
Gene ID	1791
Swiss Prot	P04053
Synonyms	Deoxynucleotidyltransferase terminal; DNA nucleotidylexotransferase; TdT; Nucleosidetriphosphate DNA deoxynucleotidylexotransferase; Terminal addition enzyme; Terminal deoxynucleotidyltransferase; Terminal transferase; TDT_HUMAN.
Background	This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008]
Application Dilution
FCM	1:20-100