Overview |
bsm-30140M-APC-CY7 |
human CD279 (PD-1)/APC-Cy7 |
FCM |
Human |
Specifications |
Unconjugated |
Mouse |
Monoclonal |
3A9 |
IgG1/Kappa |
n/a |
Affinity purified by Protein G |
0.01M PBS, 0.5%BSA, 0.03% Proclin300 |
Store at 2-8℃. Protect from light. Avoid freezing. |
Target |
5133 |
Q15116 |
Programmed cell death protein 1; CD279; CD279 antigen; hPD 1; hPD-1; hSLE1; PD 1; PD1; PDCD 1; PDCD1; PDCD1_HUMAN; Programmed cell death 1; Protein PD 1; Protein PD-1; SLEB2; Systemic lupus erythematosus susceptibility 2. |
Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020] |
Application Dilution |
FCM |
1:20-100 |