Overview |
bsm-30032M-PE |
human CD41/PE |
FCM |
Human |
Specifications |
Unconjugated |
Mouse |
Monoclonal |
7C11 |
IgG1/Kappa |
n/a |
Affinity purified by Protein G |
0.01M PBS, 0.5%BSA, 0.03% Proclin300 |
Store at 2-8℃. Protect from light. Avoid freezing. |
Target |
3674 |
Q9QUM0 |
platelet glycoprotein IIb of IIb/IIIa complex; Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); ITGA2B; GPIIb; GTA; HPA3; CD 41; CD41; CD41 antigen; CD41a; CD41b; GP2b; GPalpha IIb; GPalphaIIb; Integrin alpha IIb; Integrin alpha IIb precursor; ITGA 2B; ITGA2B; ITGAB; Platelet fibrinogen receptor alpha; Platelet fibrinogen receptor alpha subunit; Platelet glycoprotein IIb of IIb/IIIa complex; Platelet membrane glycoprotein IIb; Platelet specific antigen bak; ITA2B_HUMAN. |
This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016] |
Application Dilution |
FCM |
1:20-100 |