Overview |
bsm-30016M-PACIFIC BLUE |
human CD15 (SSEA-1)/Pacific Blue |
FCM |
Human |
Specifications |
Unconjugated |
Mouse |
Monoclonal |
15F2 |
IgG1/Kappa |
n/a |
Affinity purified by Protein G |
0.01M PBS, 0.5%BSA, 0.03% Proclin300 |
Store at 2-8℃. Protect from light. Avoid freezing. |
Target |
Stage-Specific Embryonic Antigen 1, X-hapten, Lewis X, 3-FAL, CD15, SSEA1, SSEA-1 |
The MC-480 antibody reacts with mouse and human Stage-Specific Embryonic Antigen-1 (SSEA-1). It is a Lewis blood group related carbohydrate antigen, also known as X-hapten, Lewis X, 3-FAL, 3-fucosyl-N-acetyllactosamine, or CD15. The expression pattern of SSEA-1 antigen is different in humans than in mice. In mice, SSEA-1 is expressed on embryonic stem cells (ES), embryonal carcinoma cells (EC), 8-cell to blastocyst embryos, and a subset of embryonic inner cell mass. The expression on murine ES cells is decreased upon differentiation. In humans, however, SSEA-1 is not found on undifferentiated ES cells, but its expression is upregulated along with differentiation. CD15 is highly expressed on adult human granulocytes. It has been reported that SSEA-1 plays a role in cell adhesion and regulation of cell differentiation. |
Application Dilution |
FCM |
1:20-100 |