| Overview |
| bs-13263R-PE-Cy7 |
| GAD65 + GAD67 Polyclonal Antibody, PE-Cy7 Conjugated |
| WB |
| Mouse |
| Human, Rat, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit |
| Specifications |
| PE-Cy7 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human GAD65 |
| 351-450/585 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 25722571 |
| Q05329, Q99259 |
| Cytoplasm, Cell membrane |
| Glutamate decarboxylase 2; GAD2; 65 kDa glutamic acid decarboxylase; GAD-65; Glutamate decarboxylase 65 kDa isoform; Glutamate decarboxylase 1; GAD1; 67 kDa glutamic acid decarboxylase; GAD-67; Glutamate decarboxylase 67 kDa isoform |
| This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma aminobutyric acid from L glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin dependent diabetes. This gene may also play a role in the stiff man syndrome. |
| Application Dilution |
| WB |
1:300-5000 |
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