| Overview |
| bsm-62431r-apc-cy5-100ul |
| Mono/Di/TriMethyl-Histone H3.1 (Lys15) Recombinant Monoclonal Antibody, APC-Cy5 Conjugated |
| WB, IF(ICC) |
| Human, Mouse |
| Specifications |
| APC-Cy5 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human Histone H3.1 around the methylation site of K15 |
| Lys15 |
| Monoclonal |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 8350 |
| P68431 |
| Nucleus |
| H3 histone; HIST1H3A; Histone cluster 1, H3a;H3/l; HIST3H3; H3K14me1; H3K14me2; H3K14me3. |
| Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Application Dilution |
| WB |
1:300-5000 |
| IF(ICC) |
1:50-200 |
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