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TREX1 Recombinant Monoclonal Antibody, PE-Cy3 Conjugated

Applications

  • WB

Reactivity

  • Human
Overview
Catalog # bsm-61966r-pe-cy3-100ul
Product Name TREX1 Recombinant Monoclonal Antibody, PE-Cy3 Conjugated
Applications WB
Reactivity Human
Specifications
Conjugation PE-Cy3
Host Rabbit
Source KLH conjugated synthetic peptide derived from human TREX1
Clonality Monoclonal
Clone # Recombinant
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 11277
Swiss Prot Q9NSU2
Synonyms AGS1; AGS5; CRV; DNase III; DRN3; HERNS; TREX1.
Background Major cellular 3'-to-5' DNA exonuclease which digests single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA) with mismatched 3' termini.Prevents cell-intrinsic initiation of autoimmunity.Acts by metabolizing DNA fragments from endogenous retroelements, including L1, LTR and SINE elements.
Application Dilution
WB 1:300-5000