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Cytochrome C (6B10) Monoclonal Antibody, HRP Conjugated

Applications

  • WB
  • IHC-P

Reactivity

  • Human
  • Rat
  • Rabbit
Overview
Catalog # bsm-33193M-HRP
Product Name Cytochrome C (6B10) Monoclonal Antibody, HRP Conjugated
Applications WB, IHC-P
Reactivity Human, Rat, Rabbit
Specifications
Conjugation HRP
Host Mouse
Source Recombinant human Cytochrome C Protein
Clonality Monoclonal
Clone # 6B10
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 54205
Swiss Prot P99999
Synonyms Cytochrome c; CYCS
Background Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
Application Dilution
WB
IHC-P 1:200-400