| Overview |
| bs-9767R-Biotin |
| C10orf4 Polyclonal Antibody, Biotin Conjugated |
| WB, IHC-P |
| Human, Mouse, Rat |
| Specifications |
| Biotin |
| Rabbit |
| KLH conjugated synthetic peptide derived from human C10orf4/FRA10AC1 |
| 101-200/315 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C for 12 months. |
| Target |
| Chromosome 10 open reading frame 4; F26C11.1 like; FRA10AC1; FRA10AC1 protein; Fragile site 10q23.3; PRO2972; Protein FRA10AC1; Rare folic acid type fragile site FRA10q23.3 candidate gene 1; F10C1_HUMAN. |
| C10orf4, also known as FRA10A or FRA10AC1, is a 315 amino acid nuclear protein that is expressed strongly in kidney, liver, heart, brain and skeletal muscle. Defects in the gene encoding C10orf4 are characterized by an expansion of a polymorphic CGG repeat within the 5'-UTR of the gene; an event that is thought to cause folate-sensitive fragile site FRA10A expression. Expression of this mutated FRA10A protein may be associated with tumorigenesis, neurological disorders and mental retardation. C10orf4 is believed to be conserved between species. Five isoforms of C10orf4, all of which differ in their C-termini, are expressed due to alternative splicing events. |
| Application Dilution |
| WB |
1:300-5000 |
| IHC-P |
1:200-400 |
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