Overview |
bs-9742R-PerCP-Cy5.5 |
ANGEL2 Polyclonal Antibody, PerCP-Cy5.5 Conjugated |
WB, IF(IHC-P) |
Human, Mouse, Rat |
Specifications |
PerCP-Cy5.5 |
Rabbit |
KLH conjugated synthetic peptide derived from human ANGEL2 |
61-160/544 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
90806 |
NGE2_HUMAN; Angel homolog 2; angel2; Protein angel homolog 2. |
ANGEL2 is a 544 amino acid protein that belongs to the CCR4/nocturin family and exists as two alternatively spliced isoforms. The CCR4 family of proteins are 3_5_-deadenylases that function in the first step of the degradation of poly(A) mRNA. The CCR4 family most likely displays both RNA and ssDNA substrate preferences, thereby implicating a potential role in many regulatory processes. The ANGEL2 gene maps to human chromosome 1 (1q32.3), which is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. Chromosome 1 contains about 3,000 genes, and considering the great number of genes there are also a large number of diseases associated with it. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons disease, Gaucher disease and Usher syndrome are also associated with chromosome 1. |
Application Dilution |
WB |
1:300-5000 |
IF(IHC-P) |
1:50-200 |