Overview |
bs-9083R-RBITC |
FBXW5 Polyclonal Antibody, RBITC Conjugated |
WB, IF(IHC-P) |
Human, Mouse, Rat |
Specifications |
RBITC |
Rabbit |
KLH conjugated synthetic peptide derived from human FBXW5 |
201-300/566 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
54461 |
F box and WD 40 domain containing protein 5; F box and WD repeat domain containing 5; FBW5; FBXW5_HUMAN. |
FBXW5 is a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXW5 contains WD-40 domains, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, however, they were found to be nonsense-mediated mRNA decay (NMD) candidates, hence not represented. |
Application Dilution |
WB |
1:300-5000 |
IF(IHC-P) |
1:50-200 |