Overview |
bs-8465R-PE-Cy5.5 |
APLP1 Polyclonal Antibody, PE-Cy5.5 Conjugated |
WB |
Mouse |
Human, Rat, Dog, Cow, Sheep, Horse |
Specifications |
PE-Cy5.5 |
Rabbit |
KLH conjugated synthetic peptide derived from human APLP1 |
1-100/650 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
333 |
Cytoplasm, Cell membrane |
AMYLOID BETA A4 PRECURSOR-LIKE PROTEIN 1; AMYLOID PRECURSOR-LIKE PROTEIN; Amyloid-like protein 1 precursor; APLP 1; APLP; APLP-1; Aplp1; APLP1_HUMAN; C30. |
May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I.The gamma-CTF peptide, C30, is a potent enhancer of neuronal apoptosis. |
Application Dilution |
WB |
1:300-5000 |