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Ube2H Polyclonal Antibody, PE Conjugated

Applications

  • WB

Predicted Reactivity

  • Mouse
  • Rat
  • Dog
  • Cow
  • Chicken
  • Rabbit
Overview
Catalog # bs-8370R-PE
Product Name Ube2H Polyclonal Antibody, PE Conjugated
Applications WB
Predicted Reactivity Mouse, Rat, Dog, Cow, Chicken, Rabbit
Specifications
Conjugation PE
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Ube2H/UBCH2
Immunogen Range 101-183/183
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 7328
Subcellular location Cytoplasm
Synonyms E2 20K; Ubc H2; UBC8; UBCH 2; UBCH; UBCH2; Ube2h; UBE2H_HUMAN; Ubiquitin carrier protein H; Ubiquitin conjugating enzyme E2 H; Ubiquitin conjugating enzyme E2H UBC8 homolog yeast; Ubiquitin conjugating enzyme E2H; Ubiquitin protein ligase H; Ubiquitin-conjugating enzyme E2 H; Ubiquitin-conjugating enzyme E2-20K; Ubiquitin-protein ligase H.
Background UBE2H, also known as UBC8, UBCH, UBCH2 or E2-20K, is a 183 amino acid protein involved in ubiquitin-mediated protein degradation. Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). One of several members of the ubiquitin-conjugating enzyme family, UBE2H functions as an E2 ubiquitin-conjugating enzyme that acts to catalyze the covalent attachment of ubiquitin residues to various proteins, including Histone H2A. UBE2H shares 100% identity with its mouse counterpart and 98% identity with its frog and zebrafish homologs, suggesting a conserved function between species. Multiple isoforms of UBE2H exist due to alternative splicing events.
Application Dilution
WB 1:300-5000