| Overview |
| bs-5918R-PE |
| ANGPTL3 Polyclonal Antibody, PE Conjugated |
| WB |
| Human |
| Specifications |
| PE |
| Rabbit |
| KLH conjugated synthetic peptide derived from human ANG5/ANGPTL3 |
| 21-120/460 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 27329 |
| Q9Y5C1 |
| Secreted |
| ANL3; ANG-5; FHBL2; ANGPT5; Angiopoietin-related protein 3; Angiopoietin-5; Angiopoietin-like protein 3; ANGPTL3; UNQ153/PRO179 |
| Angiopoietin-like protein 3 (Angptl3) functions as a potent lipoprotein lipase inhibitor and is an important component of plasma triglyceride homeostasis. Angptl3 also plays a role in adipose formation and angiogenesis through its interaction with integrin ?v)beta(3). It is secreted by the liver and is functionally defined by the C-terminal fibrinogen (FBN)-like domain and an N-terminal coiled-coil domain. Angptl3 regulates circulating triglyceride levels during different nutritional states thereby mediating the feeding/fasting cycle. A deficiency of Angptl3 results in abnormally low lipid levels, and a repression of the protein may be protective against atherosclerosis. Angptl3 may also play an important role in hyperlipidemia in diabetes. |
| Application Dilution |
| WB |
1:300-5000 |
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