Overview |
bs-5744R-PE-Cy5 |
CABLES2 Polyclonal Antibody, PE-Cy5 Conjugated |
WB |
Human, Mouse, Rat, Cow, Pig, Horse |
Specifications |
PE-Cy5 |
Rabbit |
KLH conjugated synthetic peptide derived from human CABLES2 |
101-200/478 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
81928 |
Cytoplasm, Nucleus, Cell membrane |
CABLES 2; Cdk5 and Abl enzyme substrate 2; Ik3 2 ; Interactor with CDK3 2; C20orf150; CABL2_HUMAN. |
CABLES2 is a proapoptotic factor involved in both p53-mediated and p53-independent apoptotic pathways. ik3-1/CABLES1, a closely related molecule, has been identified to be a candidate tumor suppressor for colon and head/neck cancers.The exact function of this protein is unknown, but it is probably involved in G1-S cell cycle transition. CABLES2 binds to CDK3, CDK5 and ABL1. |
Application Dilution |
WB |
1:300-5000 |