| Overview |
| bs-4244R-BF555 |
| Jagged 2 Polyclonal Antibody, AbBy Fluor® 555 Conjugated |
| WB |
| There is a chance that this protein will cross-react with JAG1 based on 77% sequence similarity |
| Human |
| Mouse, Rat, Dog, Cow, Pig |
| Specifications |
| AbBy Fluor® 555 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human Jagged 2 |
| 201-300/1238 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 3714 |
| Q9Y219 |
| Cell membrane |
| D12Ggc2e; HJ 2; HJ2; JAG 2; JAG2; Jagged 2 precursor; Jagged2; Syndactylism. |
| Jagged 2 is a Notch ligand involved in the mediation of Notch signaling. Jagged 2 is expressed in heart, placenta and skeletal muscle and to a lesser extend in pancreas. Very low expression in brain, lung, liver and kidney. The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. Jagged 2 is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for Jagged 2. |
| Application Dilution |
| WB |
1:300-5000 |
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