Overview |
bs-4215R-Biotin |
Sin3b Polyclonal Antibody, Biotin Conjugated |
WB, ELISA, IHC-P, IHC-F |
Human |
Mouse, Rat, Dog, Cow, Sheep, Horse, Chicken |
Specifications |
Biotin |
Rabbit |
KLH conjugated synthetic peptide derived from human Sin3b |
261-360/1162 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C for 12 months. |
Target |
23309 |
Nucleus |
SIN3 homolog B transcription regulator; Transcriptional corepressor Sin3b; SIN3B_HUMAN. |
Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. |
Application Dilution |
WB |
1:300-5000 |
ELISA |
1:500-1000 |
IHC-P |
1:200-400 |
IHC-F |
1:100-500 |