| Overview |
| bs-4191R-Biotin |
| ADAMTS4 Polyclonal Antibody, Biotin Conjugated |
| WB, ELISA, IHC-P, IHC-F |
| Due to the similarity this protein to ADAMTS1, there is a chance that this antibody may have a cross-reactivity with this protein, based upon a 73% sequence similarity in the epitope region. |
| Human, Mouse |
| Rat, Cow, Sheep, Rabbit |
| Specifications |
| Biotin |
| Rabbit |
| KLH conjugated synthetic peptide derived from human ADAMTS4 |
| 501-839/839 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C for 12 months. |
| Target |
| 9507 |
| O75173 |
| Secreted |
| ADMP-1; ADAMTS-2; ADAMTS-4; A disintegrin and metalloproteinase with thrombospondin motifs 4; ADAM-TS 4; ADAM-TS4; Aggrecanase-1; ADAMTS4; KIAA0688; UNQ769/PRO1563 |
| Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu-|-Ala-393' site. |
| Application Dilution |
| WB |
1:300-5000 |
| ELISA |
1:500-1000 |
| IHC-P |
1:200-400 |
| IHC-F |
1:100-500 |
Powered by Bioz