Overview |
bs-3012R-Biotin |
Bim(Ser87) Polyclonal Antibody, Biotin Conjugated |
WB, ELISA, IHC-P, IHC-F |
Human, Mouse, Rat |
Dog, Cow, Sheep, Pig, Horse |
Specifications |
Biotin |
Rabbit |
KLH conjugated synthetic phosphopeptide derived from human Bim around the phosphorylation site of Ser87 |
Ser87 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C for 12 months. |
Target |
10018 |
O43521 |
Cytoplasm, Cell membrane |
BAM; BIM; BOD; Bcl-2-like protein 11; Bcl2-L-11; Bcl2-interacting mediator of cell death; BCL2L11; pBIM |
Induces apoptosis and anoikis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than isoform BimEL, isoform BimL and isoform BimS. Isoform Bim-gamma induces apoptosis. Isoform Bim-alpha3 induces apoptosis possibly through a caspase-mediated pathway. Isoform BimAC and isoform BimABC lack the ability to induce apoptosis. |
Application Dilution |
WB |
1:300-5000 |
ELISA |
1:500-1000 |
IHC-P |
1:200-400 |
IHC-F |
1:100-500 |