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CCL19/MIP-3 beta Polyclonal Antibody, PE-Cy3 Conjugated

Applications

  • WB

Reactivity

  • Human
  • Rat

Predicted Reactivity

  • Mouse
  • Pig
Overview
Catalog # bs-2454R-PE-Cy3
Product Name CCL19/MIP-3 beta Polyclonal Antibody, PE-Cy3 Conjugated
Applications WB
Reactivity Human, Rat
Predicted Reactivity Mouse, Pig
Specifications
Conjugation PE-Cy3
Host Rabbit
Source KLH conjugated synthetic peptide derived from mouse CCL19
Immunogen Range 26-108/108
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 24047
Swiss Prot O70460
Subcellular location Extracellular matrix
Synonyms ELC; CKb11; MIP3B; Scya19; exodus-3; C-C motif chemokine 19; Epstein-Barr virus-induced molecule 1 ligand chemokine; EBI1 ligand chemokine; Small-inducible cytokine A19; Ccl19
Background Strongly chemotactic for naive (L-selectinhi) CD4 T-cells and for CD8 T-cells and weakly attractive for resting B-cells and memory (L-selectinlo) CD4 T-cells. May play a role in promoting encounters between recirculating T-cells and dendritic cells and in the migration of activated B-cells into the T-zone of secondary lymphoid tissues. Binds to chemokine receptor CCR7. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Application Dilution
WB 1:300-5000