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CCL19/MIP-3 beta Polyclonal Antibody, PE Conjugated

Applications

  • WB

Reactivity

  • Human
  • Rat

Predicted Reactivity

  • Mouse
  • Pig
Overview
Catalog # bs-2454R-PE
Product Name CCL19/MIP-3 beta Polyclonal Antibody, PE Conjugated
Applications WB
Reactivity Human, Rat
Predicted Reactivity Mouse, Pig
Specifications
Conjugation PE
Host Rabbit
Source KLH conjugated synthetic peptide derived from mouse CCL19
Immunogen Range 26-108/108
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 24047
Swiss Prot O70460
Subcellular location Extracellular matrix
Synonyms ELC; CKb11; MIP3B; Scya19; exodus-3; C-C motif chemokine 19; Epstein-Barr virus-induced molecule 1 ligand chemokine; EBI1 ligand chemokine; Small-inducible cytokine A19; Ccl19
Background Strongly chemotactic for naive (L-selectinhi) CD4 T-cells and for CD8 T-cells and weakly attractive for resting B-cells and memory (L-selectinlo) CD4 T-cells. May play a role in promoting encounters between recirculating T-cells and dendritic cells and in the migration of activated B-cells into the T-zone of secondary lymphoid tissues. Binds to chemokine receptor CCR7. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Application Dilution
WB 1:300-5000