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C9orf135 Polyclonal Antibody, PE Conjugated

Applications

  • WB

Predicted Reactivity

  • Human
  • Mouse
  • Rat
  • Horse
  • Rabbit
Overview
Catalog # bs-15312R-PE
Product Name C9orf135 Polyclonal Antibody, PE Conjugated
Applications WB
Predicted Reactivity Human, Mouse, Rat, Horse, Rabbit
Specifications
Conjugation PE
Host Rabbit
Source KLH conjugated synthetic peptide derived from human C9orf135
Immunogen Range 151-229/229
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 138724
Subcellular location Cytoplasm, Cell membrane
Synonyms C9orf135; CI135_HUMAN; Uncharacterized protein C9orf135.
Background C9orf135 (chromosome 9 open reading frame 135) is a 229 amino acid single-pass membrane protein encoded by a gene that maps to human chromosome 9q21.11. Chromosome 9 consists of about 145 million bases, represents 4% of the human genome and encodes nearly 900 genes. Thought to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.
Application Dilution
WB 1:300-5000