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API5 Polyclonal Antibody, Cy3 Conjugated

Applications

  • WB
  • FCM

Reactivity

  • Mouse

Predicted Reactivity

  • Human
  • Rat
  • Dog
  • Cow
  • Pig
  • Horse
  • Guinea Pig
Overview
Catalog # bs-1252R-Cy3
Product Name API5 Polyclonal Antibody, Cy3 Conjugated
Applications WB, FCM
Reactivity Mouse
Predicted Reactivity Human, Rat, Dog, Cow, Pig, Horse, Guinea Pig
Specifications
Conjugation Cy3
Host Rabbit
Source KLH conjugated synthetic peptide derived from human API5
Immunogen Range 351-460/504
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 8539
Swiss Prot Q9BZZ5
Subcellular location Cytoplasm, Nucleus
Synonyms AAC11; AAC-11; Apoptosis inhibitor 5; API-5; Antiapoptosis clone 11 protein; Cell migration-inducing gene 8 protein; Fibroblast growth factor 2-interacting factor; FIF; Protein XAGL; API5; MIG8
Background Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.
Application Dilution
WB 1:300-5000
FCM 1:20-100