| Overview |
| bs-12329R-PE |
| THEMIS Polyclonal Antibody, PE Conjugated |
| WB |
| Human, Rat |
| Mouse, Dog, Pig, Horse, Rabbit |
| Specifications |
| PE |
| Rabbit |
| KLH conjugated synthetic peptide derived from human THEMIS |
| 301-400/641 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 387357 |
| Q8N1K5 |
| Cytoplasm, Nucleus |
| GASP; SPOT; TSEPA; C6orf190; C6orf207; bA325O24.3; bA325O24.4; Protein THEMIS; Thymocyte-expressed molecule involved in selection; THEMIS |
| Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk (By similarity). |
| Application Dilution |
| WB |
1:300-5000 |
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