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Caspase 3 Polyclonal Antibody, PE Conjugated

Applications

  • WB

Reactivity

  • Human
  • Mouse
  • Rat
  • Bovine
  • Pig
  • Chicken
  • Sheep
  • Rabbit
  • Others
  • Monkey
Overview
Catalog # bs-0081R-PE
Product Name Caspase 3 Polyclonal Antibody, PE Conjugated
Applications WB
Reactivity Human, Mouse, Rat, Bovine, Pig, Chicken, Sheep, Rabbit, Others, Monkey
Specifications
Conjugation PE
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Caspase 3(Active)
Immunogen Range 1-100/277
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 836
Swiss Prot P42574
Subcellular location Cytoplasm
Synonyms CPP32; SCA-1; CPP32B; Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; CASP3
Background Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
Application Dilution
WB 1:300-5000