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GADD45 Polyclonal Antibody, PE-Cy7 Conjugated

Applications

  • WB
  • FCM

Reactivity

  • Human
  • Mouse
  • Rat

Predicted Reactivity

  • Cow
  • Pig
  • Chicken
Overview
Catalog # bs-1360R-PE-Cy7
Product Name GADD45 Polyclonal Antibody, PE-Cy7 Conjugated
Applications WB, FCM
Reactivity Human, Mouse, Rat
Predicted Reactivity Cow, Pig, Chicken
Specifications
Conjugation PE-Cy7
Host Rabbit
Source KLH conjugated synthetic peptide derived from human GADD45
Immunogen Range 65-165/165
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 1647
Swiss Prot P24522
Subcellular location Cytoplasm, Cell membrane
Synonyms DDIT1; GADD45; Growth arrest and DNA damage-inducible protein GADD45 alpha; DNA damage-inducible transcript 1 protein; DDIT-1; GADD45A
Background In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity (By similarity). Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase.
Application Dilution
WB 1:300-5000
FCM 1:20-100