| Overview |
| bs-0013R-PE-Cy5 |
| Cytochrome C Polyclonal Antibody, PE-Cy5 Conjugated |
| WB, FCM |
| Human, Mouse, Rat, Chicken, Rabbit |
| Cow, Pig, Horse, Guinea Pig |
| Specifications |
| PE-Cy5 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human Cytochrome C |
| 51-105/105 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 54205 |
| P99999 |
| Cytoplasm, Cell membrane |
| CYC; HCS; THC4; Cytochrome c; CYCS |
| Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases. |
| Application Dilution |
| WB |
1:500-2000 |
| FCM |
1:20-100 |
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