| Overview |
| bsm-61107r-a488-100ul |
| Phospho-PP2A alpha (Ser307) Recombinant Monoclonal Antibody, ALEXA FLUOR® 488 Conjugated |
| WB, IF(ICC) |
| Human, Mouse, Rat |
| Specifications |
| ALEXA FLUOR® 488 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human PP2A alpha around the phosphorylation site of S307 |
| Ser307 |
| Monoclonal |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 5515 |
| P67775 |
| Nucleus |
| eplication protein C; PP2A-alpha; Replication protein C; RP-C; PPP2CA; MGC786. |
| PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'. |
| Application Dilution |
| WB |
1:300-5000 |
| IF(ICC) |
1:50-200 |
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