Overview |
bsm-54262R |
MCM5 (9G7) Monoclonal Antibody |
WB, IHC-P |
Human, Mouse |
Specifications |
Unconjugated |
Rabbit |
Recombinant protein within C terminal human MCM5. |
Monoclonal |
9G7 |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
Store at 4C for up to 2 weeks. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Target |
4174 |
P33992 |
Cytoplasm, Nucleus |
DNA replication licensing factor MCM5; P1-CDC46; MCM5; CDC46; minichromosome maintenance complex component 5. |
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Interacts with MCMBP. |
Application Dilution |
WB |
1:300-5000 |
IHC-P |
1:200-400 |