Overview |
bsm-54046R |
ITPR1 (5G10) Monoclonal Antibody |
IHC-P |
Human, Mouse, Rat |
Specifications |
Unconjugated |
Rabbit |
Human IP3 receptor aa 1770-1900 |
Monoclonal |
5G10 |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
Store for 1 year at -20C from date of shipment. Store for 1 year at -20C from date of shipment. |
Target |
3708 |
Q14643 |
Inositol 1,4,5-trisphosphate receptor type 1, IP3 receptor isoform 1, Type 1 inositol 1,4,5-trisphosphate receptor, IP3R 1, InsP3R1, Type 1 InsP3 receptor, ITPR1, INSP3R1; IP3 Receptor. |
Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity). |
Application Dilution |
IHC-P |
1:200-400 |