Overview |
bsm-52797R |
Glucocorticoid Receptor (1C1) Monoclonal Antibody |
WB, FCM |
Human, Mouse, Rat, Zebrafish |
Specifications |
Unconjugated |
Rabbit |
Human Glucocorticoid Receptor between 1 to 150 amino acids |
Monoclonal |
1C1 |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
Store at -20°C for 12 months. |
Target |
2908 |
P04150 |
Glucocorticoid receptor, Nuclear receptor subfamily 3 group C member 1, GR, NR3C1 |
Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. May play a negative role in adipogenesis through the regulation of lipolytic and antilipogenic genes expression. |
Application Dilution |
WB |
1:300-5000 |
FCM |
1:20-100 |