Overview |
bsm-52755R |
Estrogen Receptor beta (2C2) Monoclonal Antibody |
WB |
Human |
Specifications |
Unconjugated |
Rabbit |
Recombinant human Estrogen Receptor beta between 1-100 amino acids |
Monoclonal |
2C2 |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
Store at -20°C for 12 months. |
Target |
2100 |
Q92731 |
Estrogen receptor beta, Nuclear receptor subfamily 3 group A member 2, ESR2, ER-beta |
Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual. |
Application Dilution |
WB |
1:300-5000 |