Overview |
bsm-52561R |
Junctional Adhesion Molecule 1 (7E1F) Monoclonal Antibody |
WB, IHC-P, IF(ICC) |
Human, Mouse, Rat |
Specifications |
Unconjugated |
Rabbit |
Human Junctional Adhesion Molecule 1 between 28-241 amino acids |
Monoclonal |
7E1F |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
Store at -20°C for 12 months. |
Target |
50848 |
Q9Y624 |
Cell membrane, Extracellular domain, Cell junction |
Junctional adhesion molecule A; Junctional adhesion molecule 1; Platelet F11 receptor; Platelet adhesion molecule 1; CD321; JAM-A; JAMA; JAM-1; JAM1; PAM-1; F11R |
Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus. |
Application Dilution |
WB |
1:300-5000 |
IHC-P |
1:200-400 |
IF(ICC) |
1:50-200 |