Overview |
bsm-52495R |
Estrogen Related Receptor alpha (1H13) Monoclonal Antibody |
WB, FCM |
Human, Mouse, Rat |
Specifications |
Unconjugated |
Rabbit |
Recombinant protein within Human Estrogen Related Receptor alpha aa 1-100 |
Monoclonal |
1H13 |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
Store at -20°C for 12 months. |
Target |
2101 |
P11474 |
Steroid hormone receptor ERR1, Estrogen receptor-like 1, Estrogen-related receptor alpha, Nuclear receptor subfamily 3 group B member 1, ERR-alpha, ESRRA, ERR1, ESRL1, NR3B1 |
Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle. |
Application Dilution |
WB |
1:300-5000 |
FCM |
1:20-100 |