Overview |
bsm-51700M |
BMP11 Monoclonal Antibody |
WB |
Human |
Specifications |
Unconjugated |
Mouse |
Recombinant human GDF11. |
Monoclonal |
C4F5 |
0.5ug/ul |
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target |
10220 |
O95390 |
Cytoplasm, Secreted |
GDF11; BMP 11; Bone morphogenetic protein 11; GDF 11; Growth differentiation factor 11; Growth/differentiation factor 11; GDF11_HUMAN. |
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses. |
Application Dilution |
WB |
=1:500-2000, |