ADA (8C3) Monoclonal Antibody

$Lane 1: Jurkat; Lane 2: MOLT-4; Lane 3: CCRF-CEM cell lysate at 20 \u00b5g per lane, probed with bsm-51447M ADA (608CT2.1.3) Monoclonal Antibody at 1:4000 dilution and 4\u2103 overnight incubation, followed by secondary antibody incubation for 60min at room temperature.$

Lane 1: Jurkat; Lane 2: MOLT-4; Lane 3: CCRF-CEM cell lysate at 20 \u00b5g per lane, probed with bsm-51447M ADA (608CT2.1.3) Monoclonal Antibody at 1:4000 dilution and 4\u2103 overnight incubation, followed by secondary antibody incubation for 60min at room temperature.

Applications

Reactivity

Human

Overview
Catalog #	bsm-51447M
Product Name	ADA (8C3) Monoclonal Antibody
Applications	WB
Reactivity	Human
Specifications
Conjugation	Unconjugated
Host	Mouse
Source	This ADA antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 287-314 amino acids from the C-terminal region of human ADA.
Clonality	Monoclonal
Clone #	8C3
Isotype	IgG1
Concentration	0.5ug/ul
Purification	Purified by Protein G.
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Store at -20°C for 12 months.
Target
Gene ID	100
Swiss Prot	P00813
Synonyms	Adenosine deaminase; Adenosine aminohydrolase; ADA; ADA1
Background	Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion.
Application Dilution
WB	1:300-5000