| Overview |
| bsm-51162m-100ul |
| FMR1 (8C2) Monoclonal Antibody |
| WB |
| Human |
| Specifications |
| Unconjugated |
| Mouse |
| This FMR1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 20-48 amino acids from human FMR1. |
| Monoclonal |
| 8C2 |
| IgM |
| 0.5ug/ul |
| Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
| 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C for 12 months. |
| Target |
| 2332 |
| Q06787 |
| POF; FMRP; POF1; FRAXA; Synaptic functional regulator FMR1; Fragile X mental retardation protein 1; Protein FMR-1; FMR1 |
| The protein encoded by this gene binds RNA and is
associated with polysomes. The encoded protein may be involved in
mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide
repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an
expansion to 55-230 repeats is the cause of fragile X syndrome.
Expansion of the trinucleotide repeat may also cause one form of
premature ovarian failure (POF1). Multiple alternatively spliced
transcript variants that encode different protein isoforms and
which are located in different cellular locations have been
described for this gene. |
| Application Dilution |
| WB |
1:300-5000 |
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