human IL-2/PE

Overview
Catalog #	bsm-30228A-PE
Product Name	human IL-2/PE
Applications	FCM
Reactivity	Human
Specifications
Conjugation	Unconjugated
Host	Rat
Clonality	Monoclonal
Clone #	2C8
Isotype	IgG2a/Kappa
Concentration	n/a
Purification	Affinity purified by Protein G
Storage Buffer	0.01M PBS, 0.5%BSA, 0.03% Proclin300
Storage Condition	Store at 2-8℃. Protect from light. Avoid freezing.
Target
Gene ID	3558
Swiss Prot	P60568
Synonyms	Interleukin-2; Interleukin 2; Interleukin2; T-cell growth factor; T Cell Growth Factor; Aldesleukin; IL 2; IL2; Lymphokine; POIL2; T Cell Growth Factor; TCGF; Involved in regulation of T cell clonal expansion; IL2_HUMAN.
Background	This gene is a member of the interleukin 2 (IL2) cytokine subfamily which includes IL4, IL7, IL9, IL15, IL21, erythropoietin, and thrombopoietin. The protein encoded by this gene is a secreted cytokine produced by activated CD4+ and CD8+ T lymphocytes, that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine (IL2R) is a heterotrimeric protein complex whose gamma chain is also shared by IL4 and IL7. The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Sep 2020]
Application Dilution
FCM	1:20-100