Overview |
bsm-30098M |
CD20 (HI20a) Monoclonal Antibody |
FCM |
Human |
Specifications |
Unconjugated |
Mouse |
KLH conjugated synthetic peptide derived from human CD20 |
Monoclonal |
HI20a |
IgG2a |
1ug/ul |
Purified by Protein G. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C for 12 months. |
Target |
931 |
P11836 |
Membrane |
CD20CHUMAN; B-lymphocyte antigen CD20; B-lymphocyte surface antigen B1; Bp35; Leukocyte surface antigen Leu-16; Membrane-spanning 4-domains subfamily A member 1; MS4A1; MS4A2; B1; CVID5; LEU-16; S7. |
CD20 is a non glycosylated protein with a molecular weight of 35 or 37 kDa depending on the degree of phosphorylation. Although not a member of the tetraspanin superfamily of cell surface receptors, it crosses the cell membrane four times. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca++ channel subunit.
|
Application Dilution |
FCM |
1:20-100 |