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human CD15 (SSEA-1)/Pacific Blue

Applications

  • FCM

Reactivity

  • Human
Overview
Catalog # bsm-30016M-PACIFIC BLUE
Product Name human CD15 (SSEA-1)/Pacific Blue
Applications FCM
Reactivity Human
Specifications
Conjugation Unconjugated
Host Mouse
Clonality Monoclonal
Clone # 15F2
Isotype IgG1/Kappa
Concentration n/a
Purification Affinity purified by Protein G
Storage Buffer 0.01M PBS, 0.5%BSA, 0.03% Proclin300
Storage Condition Store at 2-8℃. Protect from light. Avoid freezing.
Target
Synonyms Stage-Specific Embryonic Antigen 1, X-hapten, Lewis X, 3-FAL, CD15, SSEA1, SSEA-1
Background The MC-480 antibody reacts with mouse and human Stage-Specific Embryonic Antigen-1 (SSEA-1). It is a Lewis blood group related carbohydrate antigen, also known as X-hapten, Lewis X, 3-FAL, 3-fucosyl-N-acetyllactosamine, or CD15. The expression pattern of SSEA-1 antigen is different in humans than in mice. In mice, SSEA-1 is expressed on embryonic stem cells (ES), embryonal carcinoma cells (EC), 8-cell to blastocyst embryos, and a subset of embryonic inner cell mass. The expression on murine ES cells is decreased upon differentiation. In humans, however, SSEA-1 is not found on undifferentiated ES cells, but its expression is upregulated along with differentiation. CD15 is highly expressed on adult human granulocytes. It has been reported that SSEA-1 plays a role in cell adhesion and regulation of cell differentiation.
Application Dilution
FCM 1:20-100