Overview |
bs-9060R-APC-Cy7 |
DVL2 (Thr224) Polyclonal Antibody, APC-Cy7 Conjugated |
WB, IF(IHC-P) |
This antibody will recognize DVL3 when phosphorylated at Thr205 |
Human, Mouse, Rat |
Specifications |
APC-Cy7 |
Rabbit |
KLH conjugated synthetic phosphopeptide derived from human DVL2 around the phosphorylation site of Thr224 |
Thr224 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
1856 |
O14641 |
Cytoplasm |
Segment polarity protein dishevelled homolog DVL-2; Dishevelled-2; DSH homolog 2; DVL2 |
Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes (By similarity). |
Application Dilution |
WB |
1:300-5000 |
IF(IHC-P) |
1:50-200 |