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Isohelenin

Overview
Catalog # bs-83116c-5-mg
Product Name Isohelenin
Specifications
Storage Buffer White solid
Storage Condition -20°C
Target
Product Information A sesquiterpene lactone isolated from Mexican Indian medicinal plants known to have anti-inflammatory properties. A potent inhibitor of NFB (complete inhibition at 5 M)1 acting via inhibition of IKK6. Isohelenin-mediated NFB inhibition suppresses IL-8 expression2, iNOS expression3 and RANTES biosynthesis4. Displays protective effects in endotoxic shock in rodent models.5 Induces apoptosis in glioma cells.6
Description CAS Number: 470-17-7

Chemical Name: (3aR,8aR,9aR)-8a-methyl-3,5-dimethylenedecahydronaphtho[2,3-b]furan-2(3H)-one

Molecular weight: 232.32

Formula: C15H20O2

Solubility: DMSO (50 mg/ml) Ethanol (30 mg/ml)

Physical Properties: White solid

Purity: 98% by TLC NMR (Conforms)