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Filgotinib

Overview
Catalog # bs-83097c-5-mg
Product Name Filgotinib
Specifications
Storage Buffer Yellow solid
Storage Condition -20°C
Target
Product Information Potent and selective JAK1 inhibitor (IC50s=10, 28, 810 and 116 nM for JAK1, JAK2, JAK3 and TYK2 respectively.2 Displays potent anti-inflammatory activity in various models.1,2 Effective as a monotherapy in patients with active rheumatoid arthritis.3 Reverses oncostatin M-mediated inhibition of rat stem Leydig cell differentiation.4
Description CAS Number: 1206161-97-8

Chemical Name: N-[5-[4-[(1,1-dioxido-4-thiomorpholinyl)methyl]phenyl][1,2,4]triazolo[1,5-ɑ]pyridin-2-yl]-cyclopropanecarboxamide

Molecular weight: 425.50

Formula: C21H23N5O3S

Solubility: DMSO (15 mg/ml)

Physical Properties: Off-white solid

Purity: 98% by TLC, NMR (Conforms)